Bioinformatics Framework at Organism Level

Traditional bioinformatics is mostly about some 1-D linear sequences of gene, protein. A lot of efforts have been done to establish the databases, to design better searching algorithm or match system, etc. Many things in biology, however, cannot be expressed in 1-D sequences, such as the organism. It has a 3-D pattern. The frameworks at organism level can help us to understand the function of gene. We can “compare precisely the patterns of expression of different genes” by them. Some groups have done a lot of work about it . I will focus on the digital frameworks for embryonic development.